Jeremy Lowe, Vaishnavi Prathap, Akito Kamei, Sidhartha Giri, Krushna Chandra Sahoo, Michael Kremer, Elisa M Maffioli, Amy J. Pickering
Publications
CEND affiliates and fellows are research leaders - publishing new discoveries to accelerate progress against neglected and emerging diseases.
Bridge recombinase enables versatile rewriting of bacterial genomes
Jaymin Patel, Sophia E. Swartz, Agnes Oromi-Bosch, Liana Yong, Zachary W. LaTurner, Jack E. Demaray, Angela Voelker, Ryuichi Ono, Patrick Vu, Preeti Rao, Hannah Luskin, Pia Andrade, Michael L. Cui, Givi Mchedlishvili, Madeline M. Hayes, Natalie Aluwihare, Carlos E. Iglesias-Aguirre, Emma C. MacKenzie, Cynthia I. Rodriguez, Suzanne Devkota, Spencer Diamond, Brady F. Cress
Double-edged sword: flavivirus NS1 enhances human plasmin-mediated fibrinolysis while being targeted for cleavage and inactivation
Lucas Mendes-Monteiro, Pedro Henrique Carneiro, Jonas N. Conde, Joice L. Menezes, Matheus Silva de Souza, Pedro F. de Carvalho, Eugenio D. Hottz, Eva Harris, Diego Allonso, Ronaldo Mohana-Borges
Abundance of the vector Aedes aegypti in urban and rural areas in Managua, Nicaragua
Harold Suazo-Laguna, Jacqueline Mojica-Díaz, María M Lopez, Angel Balmaseda, Eva Harris, Josefina Coloma, Jose G Juarez
Phylogenetic diversity, functional pathways, and network interactions of ocular chlamydia-like organisms (CLOs) in trachoma-endemic Ethiopia
Olusola Olagoke, Xinhe Zheng, Seongwon Chung, Hiwot Degineh Mengistie, Kaleb Asfaha, Timothy D Read, Deborah Dean
A Monovalent SMAC Mimetic as a Potential Host-Directed Therapy for Tuberculosis
Jiahong Ji, Xiaoyi Jiang, Xinlei Liao, Fengjiao Du, Guirong Wang, Hairong Huang, Miao Mei, Yuan He, Xu Tan, Babak Javid, Hao Li
Examining the effect of neighborhood sanitation coverage on childhood diarrheal disease in rural Bangladesh
Hannah Van Wyk, Andrew F Brouwer, Jesse Contreras, Mahbubur Rahman, Mahfuza Islam, Amy J Pickering, Benjamin F Arnold, Stephen P Luby, John M Colford, Matthew Freeman, Ayse Ercumen, Joseph NS Eisenberg
Non‐cognate CD8 Binding to MHC I Promotes Positive Selection of an MHC‐E Restricted CD8 T Cell Population
Xiaokun Yang, Melissa A Colden, Rachel Coombs, Kathya Arana, Dan Tran, Michael Manoharan Valerio, Ellen A Robey, Laurent Coscoy
Harnessing evolution: leveraging bacterial isoprenoid pathway diversity toward improved bioengineering strategies
Christine M. Qabar, Bailey A. Marshall, Robert Landick, Jeffery S. Cox
Global population structures and demographic history of Suillus luteus, a pine co‐introduced ectomycorrhizal fungus associated with exotic forestry and invasion
Yi‐Hong Ke, Anna Bazzicalupo, Joske Ruytinx, Lotus Lofgren, Thomas Bruns, Sara Branco, Brian Looney, Dai Hirose, Leho Tedersoo, Ursula Peintner, J Alejandro Rojas, Hui‐Ling Liao, Jonathan M Plett, Ian C Anderson, Anna Lipzen, Alan Kuo, Kerrie Barry, Igor Grigoriev, Jason D Hoeksema, Peter G Kennedy, Nhu H Nguyen, Rytas Vilgalys
[HTML] from nature.com Get it at UC Co-speciation and host-switching drives diversity of picornaviruses and sapoviruses in Malagasy fruit bats
Gwenddolen Kettenburg, Hafaliana C Ranaivoson, Angelo Andrianiaina, Santino Andry, Amy R Henry, Rachel L Davis, Farida Laboune, Elizabeth R Longtine, Sucheta Godbole, Sophia Horigan, Emily Cornelius Ruhs, Vololoniaina Raharinosy, Tsiry Hasina Randriambolamanantsoa, Vincent Lacoste, Jean-Michel Heraud, Philippe Dussart, Daniel C Douek, Cara E Brook
Cross-variant immune shield: computational multiepitope vaccine design against B. 617.2 to Omicron sub-lineages in SARS-CoV-2
Jinal M Thakor, Unnati V Panchal, Dhaval Patel, Slawomir Filipek, Urszula Orzeł, Ramasamy Paulmurugan, Katja Hanack, Dorian Liepmann, Venkatesan Renugopalakrishnan, Chaitanya G Joshi, Madhvi Joshi
Identification of proteins influencing CRISPR-associated transposases for enhanced genome editing
Leo CT Song, Amanda TP Alker, Agnès Oromí-Bosch, Sophia E Swartz, Jonathan NV Martinson, Jigyasa Arora, Abby M Wang, Rachel Rovinsky, Sara J Smith, Emily C Pierce, Adam M Deutschbauer, Jennifer A Doudna, Brady F Cress, Benjamin E Rubin
Structural Characterization and AI‐Enhanced Modeling of a Broadly Neutralizing Camelid Antibody Against SARS‐CoV‐2 Variants
Katja Hanack, Urszula Orzeł, Anja Schlör, Sourabh Mehta, Anandi Krishnan, Slawomir Filipek, Rushika Patel, Madhvi Joshi, Markus Hoffmann, Stefan Pöhlmann, Chaitanya Joshi, Dorian Liepmann, Ramasamy Paulmurugan, Venkatesan Renugopalakrishnan
Target cell tension regulates macrophage trogocytosis [Pre-print]
Daniel Fletcher, Caitlin Cornell, Aymeric Chorlay, Deepak Krishnamurthy, Nicholas Martin, Lucia Baldauf
Rainfall and temperature influence effectiveness of on-site sanitation intervention against E. coli contamination in Bangladeshi households
Caitlin G Niven, Mahfuza Islam, Anna Nguyen, Andrew Mertens, Amy J Pickering, Laura H Kwong, Mahfuja Alam, Debashis Sen, Sharmin Islam, Mahbubur Rahman, Leanne Unicomb, Alan E Hubbard, Stephen P Luby, Jessica A Grembi, John M Colford Jr, Benjamin F Arnold, Jade Benjamin-Chung, Ayse Ercumen
Longitudinal single cell multi-omic profiling of Nicaraguan children reveals trajectories of pediatric immune development and variation 2840
Leon Bichmann, Nicholas Rachmaninoff, Stephen Popper, Neha Bansal, Galina Koroleva, Can Liu, Andrew Martins, Lionel Gresh, Jose Victor Zambrana, Aubree Gordon, Philip Johnson, Guillermina Kuan, Angel Balmaseda, Eva Harris, John Tsang
Diverse infection models demonstrate robust resistance of Mycobacterium tuberculosis to innate immunity [Pre-print]
Marian R Fairgrieve, Ella C Brydon, Roberto A Chavez, Dmitri I Kotov, Russell E Vance
Multiple roads lead to Rome: B cell imprinting in distinct sequential flavivirus infections reveals different pathways to acquiring virus-neutralizing antibodies 4434
Tulika Singh, Sandra Bos, Gerald Vásquez Alemán, Tiffany Kim, Miriam Walter, Nharae Lee, Elias Duarte, Aaron Graber, Amir Balakhmet, José Victor Zambrana, Jorge Ruiz Salinas, Federico Narvaez, Angel Balmaseda, Eun-Young Kim, Steven Wolinsky, Eva Harris
Dynamics of antibody responses following primary dengue virus 3 infections in Nicaragua reveals differential waning of IgG responses by antigen and subclass 3546
Aquena Hana Ball, Elias Duarte, José Victor Zambrana, Sandra Bos, Agamjot Bal, Marco Antonio Chapa, Claudia Sanchez San Martin, Guillermina Kuan, Angel Balmaseda, Eva Harris