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Publications

CEND affiliates and fellows are research leaders - publishing new discoveries to accelerate progress against neglected and emerging diseases.

Publications

Modified Anti-PstS1 Bi-specific antibodies unlock potent protection against tuberculosis

Akanksha, Rania Bouzeyen, Avia Watson, Gil Wiseglass, Nyaradzai Sithole, Lilach Abramovitz, Noam Ben-Shalom, Rotem Rubinstein, Babak Javid, Natalia T Freund

Prior contact lens wear reduces susceptibility of the superficially-injured cornea to bacterial adhesion

Yujia Yang, Orneika Flandrin, Sara J Abboud, Eric Jedel, David J Evans, Suzanne MJ Fleiszig

Dengue transmission risk in California under climate and land-use change: a semi-mechanistic modelling study

Lisa I Couper, Terrell J Sipin, Samantha Sambado, Zoe Rennie, Kyle M Shanebeck, Kelsey P Lyberger, Philip PA Collender, Van Ngo, Justin V Remais, Andrew J MacDonald

A bidirectional nanAKE locus enables sialic acid catabolism in gut microbiome member Hungatella hathewayi

Vienvilay Phandanouvong-Lozano, Letizia Pastore, Gabriel Miller, Kathryn Y Lin, Ashley R Wolf

Cas9+ conditionally immortalized neutrophil progenitors as a tool for genome-wide CRISPR screening for neutrophil differentiation and function

Robyn M Jong, Krystal L Ching, Nicholas E Garelis, Alex Zilinskas, Xammy Huu Wrynla, Sagar Rawal, Bianca C Hill, Bridget A Luckie, Lillian Shallow, Jeffery S Cox, Gregory M Barton, Sarah A Stanley

Extensive cryptic circulation sustains mpox among men who have sex with men

Joseph A. Lewnard, Miguel I. Paredes, Matan Yechezkel, Gregg S. Davis, Vennis Hong, Jessica Skela, Utsav Pandey, Noah T. Parker, Lauren C. Granskog, Magdalena E. Pomichowski, Iris Anne C. Reyes, Isabel Rodriguez-Barraquer, Nicola F. Müller, Sara Y. Tartof 
 

SmileyLlama: modifying large language models for directed chemical space exploration

Joseph M Cavanagh, Kunyang Sun, Andrew Gritsevskiy, Dorian Bagni, Yingze Wang, Thomas D Bannister, Teresa Head-Gordon

Localized heme sensing through a ternary molecular glue

Michael Heider, Clara Hipp, Zhi Yang, Han Xiao, Tobias Beschauner, Eddie Wehri, Wencke Walter, Rumi Sherriff, Srividya Chandrasekhar, Torsten Haferlach, Julia Schaletzky, Michael Rape

Low-dose Inorganic Arsenic Exposure Reprograms Macrophages Differentiation and Function Toward Tumor-promoting Phenotypes

Emily J Illingworth, Sylvia S Sanchez, Kristal A Rychlik, Andre Kleensang, Jason Laird, Gabriel A Lopez-Cecetaite, M Carolina Rodriguez Steube, Aakriti Mathur, Pritam Sadhukhan, Daniel A Medina-Cleghorn, Daniel Nomura, Martyn T Smith, Mohammad O Hoque, Fenna CM Sillé

Epidemiological impacts of nonpharmaceutical interventions are modulated by immunity exposure trade offs

Chadi M Saad-Roy, Bjarke Frost Nielsen, Margaret L Lind, Caroline E Wagner, Arne Traulsen, C Jessica E Metcalf, Mike Boots, Derek AT Cummings, Bryan T Grenfell

Economic costs of TB and HIV in high-TB-burden countries

Manuel Barron, Stefano Bertozzi, Paul Gertler

Double-edged sword: flavivirus NS1 enhances human plasmin-mediated fibrinolysis while being targeted for cleavage and inactivation

Lucas Mendes-Monteiro, Pedro Henrique Carneiro, Jonas N. Conde, Joice L. Menezes, Matheus Silva de Souza, Pedro F. de Carvalho, Eugenio D. Hottz, Eva Harris, Diego Allonso, Ronaldo Mohana-Borges

In-line chlorination for drinking water in rural Odisha, India: A randomized controlled implementation trial

Jeremy Lowe, Vaishnavi Prathap, Akito Kamei, Sidhartha Giri, Krushna Chandra Sahoo, Michael Kremer, Elisa M Maffioli, Amy J. Pickering

Abundance of the vector Aedes aegypti in urban and rural areas in Managua, Nicaragua

Harold Suazo-Laguna, Jacqueline Mojica-Díaz, María M Lopez, Angel Balmaseda, Eva Harris, Josefina Coloma, Jose G Juarez

Phylogenetic diversity, functional pathways, and network interactions of ocular chlamydia-like organisms (CLOs) in trachoma-endemic Ethiopia

Olusola Olagoke, Xinhe Zheng, Seongwon Chung, Hiwot Degineh Mengistie, Kaleb Asfaha, Timothy D Read, Deborah Dean

Examining the effect of neighborhood sanitation coverage on childhood diarrheal disease in rural Bangladesh

Hannah Van Wyk, Andrew F Brouwer, Jesse Contreras, Mahbubur Rahman, Mahfuza Islam, Amy J Pickering, Benjamin F Arnold, Stephen P Luby, John M Colford, Matthew Freeman, Ayse Ercumen, Joseph NS Eisenberg

Harnessing evolution: leveraging bacterial isoprenoid pathway diversity toward improved bioengineering strategies

Christine M. Qabar, Bailey A. Marshall, Robert Landick, Jeffery S. Cox

Target cell tension regulates macrophage trogocytosis [Pre-print]

Daniel Fletcher, Caitlin Cornell, Aymeric Chorlay, Deepak Krishnamurthy, Nicholas Martin, Lucia Baldauf

Rainfall and temperature influence effectiveness of on-site sanitation intervention against E. coli contamination in Bangladeshi households

Caitlin G Niven, Mahfuza Islam, Anna Nguyen, Andrew Mertens, Amy J Pickering, Laura H Kwong, Mahfuja Alam, Debashis Sen, Sharmin Islam, Mahbubur Rahman, Leanne Unicomb, Alan E Hubbard, Stephen P Luby, Jessica A Grembi, John M Colford Jr, Benjamin F Arnold, Jade Benjamin-Chung, Ayse Ercumen